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Inhibiting citrullination in rheumatoid arthritis: taking fuel from the fire

Citrullination is a post-translational modification catalysed by peptidylarginine deiminase and is a common feature of inflammation. The presence of anti-citrullinated protein/peptide antibodies (ACPA), however, is unique to rheumatoid arthritis. Several lines of evidence suggest that ACPA are impor...

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Detalles Bibliográficos
Autores principales: Fisher, Benjamin AC, Venables, Patrick J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392831/
https://www.ncbi.nlm.nih.gov/pubmed/22380578
http://dx.doi.org/10.1186/ar3740