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Large-scale prediction of adverse drug reactions using chemical, biological, and phenotypic properties of drugs

OBJECTIVE: Adverse drug reaction (ADR) is one of the major causes of failure in drug development. Severe ADRs that go undetected until the post-marketing phase of a drug often lead to patient morbidity. Accurate prediction of potential ADRs is required in the entire life cycle of a drug, including e...

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Detalles Bibliográficos
Autores principales: Liu, Mei, Wu, Yonghui, Chen, Yukun, Sun, Jingchun, Zhao, Zhongming, Chen, Xue-wen, Matheny, Michael Edwin, Xu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392844/
https://www.ncbi.nlm.nih.gov/pubmed/22718037
http://dx.doi.org/10.1136/amiajnl-2011-000699