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Large-scale prediction of adverse drug reactions using chemical, biological, and phenotypic properties of drugs
OBJECTIVE: Adverse drug reaction (ADR) is one of the major causes of failure in drug development. Severe ADRs that go undetected until the post-marketing phase of a drug often lead to patient morbidity. Accurate prediction of potential ADRs is required in the entire life cycle of a drug, including e...
Autores principales: | Liu, Mei, Wu, Yonghui, Chen, Yukun, Sun, Jingchun, Zhao, Zhongming, Chen, Xue-wen, Matheny, Michael Edwin, Xu, Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392844/ https://www.ncbi.nlm.nih.gov/pubmed/22718037 http://dx.doi.org/10.1136/amiajnl-2011-000699 |
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