Damage-Induced Phosphorylation of Sld3 is Important to Block Late Origin Firing

Origins of replication are activated throughout S-phase such that some origins fire early and others fire late to ensure that each chromosome is completely replicated in a timely fashion. However, in response to DNA damage or replication fork stalling, eukaryotic cells block activation of unfired or...

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Detalles Bibliográficos
Autores principales: Lopez-Mosqueda, Jaime, Maas, Nancy L., Jonsson, Zophonias O., DeFazio Eli, Lisa G., Wohlschlegel, James, Toczyski, David P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393088/
https://www.ncbi.nlm.nih.gov/pubmed/20865002
http://dx.doi.org/10.1038/nature09377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393088/
https://www.ncbi.nlm.nih.gov/pubmed/20865002
http://dx.doi.org/10.1038/nature09377

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