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Damage-Induced Phosphorylation of Sld3 is Important to Block Late Origin Firing
Origins of replication are activated throughout S-phase such that some origins fire early and others fire late to ensure that each chromosome is completely replicated in a timely fashion. However, in response to DNA damage or replication fork stalling, eukaryotic cells block activation of unfired or...
Autores principales: | Lopez-Mosqueda, Jaime, Maas, Nancy L., Jonsson, Zophonias O., DeFazio Eli, Lisa G., Wohlschlegel, James, Toczyski, David P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393088/ https://www.ncbi.nlm.nih.gov/pubmed/20865002 http://dx.doi.org/10.1038/nature09377 |
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