Genetic, host, and environmental interactions in a 19 year old with severe chronic obstructive lung disease; observations regarding the pathophysiology of airflow obstruction

A case of a 19-year-old with severe chronic obstructive pulmonary disease is presented. This case illustrates genetic (severe alpha-1 antitrypsin deficiency) and host factors (such as developmental diaphragmatic hernia and the innate response to injury), and environmental (high oxidative stress and...

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Detalles Bibliográficos
Autores principales: Grosu, Horiana B, Killam, Jonathan, Khusainova, Elvina, Lozada, James, Needelman, Andrew, Eden, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393337/
https://www.ncbi.nlm.nih.gov/pubmed/22791992
http://dx.doi.org/10.2147/COPD.S30325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393337/
https://www.ncbi.nlm.nih.gov/pubmed/22791992
http://dx.doi.org/10.2147/COPD.S30325

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