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Ribozyme-mediated gene knock down strategy to dissect the consequences of PDGF stimulation in vascular smooth muscle cells

BACKGROUND: Vascular Smooth Muscle Cells (VSMCs), due to their plasticity and ability to shift from a physiological contractile-quiescent phenotype to a pathological proliferating-activated status, play a central role in the onset and progression of atherosclerosis and cardiovascular diseases. PDGF-...

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Detalles Bibliográficos
Autores principales: Lande, Caterina, Boccardi, Claudia, Citti, Lorenzo, Mercatanti, Alberto, Rizzo, Milena, Rocchiccioli, Silvia, Tedeschi, Lorena, Trivella, Maria Giovanna, Cecchettini, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393606/
https://www.ncbi.nlm.nih.gov/pubmed/22676333
http://dx.doi.org/10.1186/1756-0500-5-268