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The gamma-aminobutyric acid type B (GABA(B)) receptor agonist baclofen inhibits morphine sensitization by decreasing the dopamine level in rat nucleus accumbens
BACKGROUND: Repeated morphine exposure can induce behavioral sensitization. There are evidences have shown that central gamma-aminobutyric acid (GABA) system is involved in morphine dependence. However, the effect of a GABA(B) receptor agonist baclofen on morphine-induced behavioral sensitization in...
Autores principales: | Fu, Zhenyu, Yang, Hongfa, Xiao, Yuqiang, Zhao, Gang, Huang, Haiyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393629/ https://www.ncbi.nlm.nih.gov/pubmed/22559224 http://dx.doi.org/10.1186/1744-9081-8-20 |
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