Trypanosoma brucei gambiense Group 1 Is Distinguished by a Unique Amino Acid Substitution in the HpHb Receptor Implicated in Human Serum Resistance

Trypanosoma brucei rhodesiense (Tbr) and T. b. gambiense (Tbg), causative agents of Human African Trypanosomiasis (sleeping sickness) in Africa, have evolved alternative mechanisms of resisting the activity of trypanosome lytic factors (TLFs), components of innate immunity in human serum that protec...

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Detalles Bibliográficos
Autores principales: Symula, Rebecca E., Beadell, Jon S., Sistrom, Mark, Agbebakun, Kehinde, Balmer, Oliver, Gibson, Wendy, Aksoy, Serap, Caccone, Adalgisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393672/
https://www.ncbi.nlm.nih.gov/pubmed/22802982
http://dx.doi.org/10.1371/journal.pntd.0001728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393672/
https://www.ncbi.nlm.nih.gov/pubmed/22802982
http://dx.doi.org/10.1371/journal.pntd.0001728

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