Mouse-Adapted H9N2 Influenza A Virus PB2 Protein M147L and E627K Mutations Are Critical for High Virulence

H9N2 influenza viruses have been circulating worldwide in multiple avian species and have repeatedly infected humans to cause typical disease. The continued avian-to-human interspecies transmission of H9N2 viruses raises concerns about the possibility of viral adaption with increased virulence for h...

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Detalles Bibliográficos
Autores principales: Wang, Jingjing, Sun, Yipeng, Xu, Qi, Tan, Yuanyuan, Pu, Juan, Yang, Hanchun, Brown, Earl G., Liu, Jinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393695/
https://www.ncbi.nlm.nih.gov/pubmed/22808250
http://dx.doi.org/10.1371/journal.pone.0040752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393695/
https://www.ncbi.nlm.nih.gov/pubmed/22808250
http://dx.doi.org/10.1371/journal.pone.0040752

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