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Retinal Astrocytes Pretreated with NOD2 and TLR2 Ligands Activate Uveitogenic T Cells
On entering the tissues, infiltrating autoreactive T cells must be reactivated locally to gain pathogenic activity. We have previously reported that, when activated by Toll-like receptor 3 (TLR3) and TLR4 ligands, retinal astrocytes (RACs) are able to function as antigen-presenting cells to re-activ...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393697/ https://www.ncbi.nlm.nih.gov/pubmed/22808176 http://dx.doi.org/10.1371/journal.pone.0040510 |