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Retinal Astrocytes Pretreated with NOD2 and TLR2 Ligands Activate Uveitogenic T Cells

On entering the tissues, infiltrating autoreactive T cells must be reactivated locally to gain pathogenic activity. We have previously reported that, when activated by Toll-like receptor 3 (TLR3) and TLR4 ligands, retinal astrocytes (RACs) are able to function as antigen-presenting cells to re-activ...

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Detalles Bibliográficos
Autores principales: Jiang, Guomin, Sun, Deming, Kaplan, Henry J., Shao, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393697/
https://www.ncbi.nlm.nih.gov/pubmed/22808176
http://dx.doi.org/10.1371/journal.pone.0040510