Fool's Gold: Why Imperfect Reference Tests Are Undermining the Evaluation of Novel Diagnostics: A Reevaluation of 5 Diagnostic Tests for Leptospirosis

Background. We observed that some patients with clinical leptospirosis supported by positive results of rapid tests were negative for leptospirosis on the basis of our diagnostic gold standard, which involves isolation of Leptospira species from blood culture and/or a positive result of a microscopi...

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Detalles Bibliográficos
Autores principales: Limmathurotsakul, Direk, Turner, Elizabeth L., Wuthiekanun, Vanaporn, Thaipadungpanit, Janjira, Suputtamongkol, Yupin, Chierakul, Wirongrong, Smythe, Lee D., Day, Nicholas P. J., Cooper, Ben, Peacock, Sharon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Articles and Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393707/
https://www.ncbi.nlm.nih.gov/pubmed/22523263
http://dx.doi.org/10.1093/cid/cis403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393707/
https://www.ncbi.nlm.nih.gov/pubmed/22523263
http://dx.doi.org/10.1093/cid/cis403

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