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Splicing of the rSlo Gene Affects the Molecular Composition and Drug Response of Ca(2+)-Activated K(+) Channels in Skeletal Muscle

The molecular composition and drug responses of calcium-activated K(+) (BK) channels of skeletal muscle are unknown. Patch-clamp experiments combined with transcript scanning of the Kcnma1 gene encoding the alpha subunit of the BK channel were performed in rat slow-twitch soleus (Sol) and fast-twitc...

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Detalles Bibliográficos
Autores principales: Dinardo, Maria Maddalena, Camerino, Giulia, Mele, Antonietta, Latorre, Ramon, Conte Camerino, Diana, Tricarico, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3393747/
https://www.ncbi.nlm.nih.gov/pubmed/22808126
http://dx.doi.org/10.1371/journal.pone.0040235