Differential Impact of Cysteine Cathepsins on Genetic Mouse Models of De novo Carcinogenesis: Cathepsin B as Emerging Therapeutic Target

Lysosomal cysteine cathepsins belong to a family of 11 human proteolytic enzymes. Some of them correlate with progression in a variety of cancers and therefore are considered as potential therapeutic targets. Until recently, the contribution of individual cathepsins to tumorigenesis and tumor progre...

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Detalles Bibliográficos
Autores principales: Reinheckel, Thomas, Peters, Christoph, Krüger, Achim, Turk, Boris, Vasiljeva, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394080/
https://www.ncbi.nlm.nih.gov/pubmed/22798952
http://dx.doi.org/10.3389/fphar.2012.00133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394080/
https://www.ncbi.nlm.nih.gov/pubmed/22798952
http://dx.doi.org/10.3389/fphar.2012.00133

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