Thailandepsins are new small molecule class I HDAC inhibitors with potent cytotoxic activity in ovarian cancer cells: a preclinical study of epigenetic ovarian cancer therapy

BACKGROUND: New treatment strategies are emerging to target DNA damage response pathways in ovarian cancer. Our group has previously shown that the class I biased HDAC inhibitor romidepsin (FK228) induces DNA damage response and has potent cytotoxic effects in ovarian cancer cells. Here, we investig...

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Detalles Bibliográficos
Autores principales: Wilson, Andrew J, Cheng, Yi-Qiang, Khabele, Dineo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394212/
https://www.ncbi.nlm.nih.gov/pubmed/22531354
http://dx.doi.org/10.1186/1757-2215-5-12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394212/
https://www.ncbi.nlm.nih.gov/pubmed/22531354
http://dx.doi.org/10.1186/1757-2215-5-12

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