The NALP3 inflammasome is involved in neurotoxic prion peptide-induced microglial activation

BACKGROUND: Prion diseases are neurodegenerative disorders characterized by the accumulation of an abnormal disease-associated prion protein, PrP(Sc). In prion-infected brains, activated microglia are often present in the vicinity of PrP(Sc) aggregates, and microglial activation is thought to play a...

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Detalles Bibliográficos
Autores principales: Shi, Fushan, Yang, Lifeng, Kouadir, Mohammed, Yang, Yang, Wang, Jihong, Zhou, Xiangmei, Yin, Xiaomin, Zhao, Deming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394218/
https://www.ncbi.nlm.nih.gov/pubmed/22531291
http://dx.doi.org/10.1186/1742-2094-9-73

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394218/
https://www.ncbi.nlm.nih.gov/pubmed/22531291
http://dx.doi.org/10.1186/1742-2094-9-73

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