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BiForce Toolbox: powerful high-throughput computational analysis of gene–gene interactions in genome-wide association studies

Genome-wide association studies (GWAS) have discovered many loci associated with common disease and quantitative traits. However, most GWAS have not studied the gene–gene interactions (epistasis) that could be important in complex trait genetics. A major challenge in analysing epistasis in GWAS is t...

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Detalles Bibliográficos
Autores principales: Gyenesei, Attila, Moody, Jonathan, Laiho, Asta, Semple, Colin A.M., Haley, Chris S., Wei, Wen-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394281/
https://www.ncbi.nlm.nih.gov/pubmed/22689639
http://dx.doi.org/10.1093/nar/gks550