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A new in vivo model to test anti-tuberculosis drugs using fluorescence imaging

OBJECTIVES: The current method for testing new drugs against tuberculosis in vivo is the enumeration of bacteria in organs by cfu assay. Owing to the slow growth rate of Mycobacterium tuberculosis (Mtb), these assays can take months to complete. Our aim was to develop a more efficient, fluorescence-...

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Detalles Bibliográficos
Autores principales: Zelmer, Andrea, Carroll, Paul, Andreu, Nuria, Hagens, Kristine, Mahlo, Jacqueline, Redinger, Natalja, Robertson, Brian D., Wiles, Siouxsie, Ward, Theresa H., Parish, Tanya, Ripoll, Jorge, Bancroft, Gregory J., Schaible, Ulrich E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394442/
https://www.ncbi.nlm.nih.gov/pubmed/22635525
http://dx.doi.org/10.1093/jac/dks161