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A matrix metalloprotease-PAR1 system regulates vascular integrity, systemic inflammation and death in sepsis
Sepsis is a deadly disease characterized by the inability to regulate the inflammatory–coagulation response in which the endothelium plays a key role. The cause of this perturbation remains poorly understood and has hampered the development of effective therapeutics. Matrix metalloproteases (MMPs) a...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394510/ https://www.ncbi.nlm.nih.gov/pubmed/21591259 http://dx.doi.org/10.1002/emmm.201100145 |