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Insight into Temperature Dependence of GTPase Activity in Human Guanylate Binding Protein-1

Interferon-γ induced human guanylate binding protein-1(hGBP1) belongs to a family of dynamin related large GTPases. Unlike all other GTPases, hGBP1 hydrolyzes GTP to a mixture of GDP and GMP with GMP being the major product at 37°C but GDP became significant when the hydrolysis reaction was carried...

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Detalles Bibliográficos
Autores principales: Rani, Anjana, Pandita, Esha, Rahman, Safikur, Deep, Shashank, Sau, Apurba Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394710/
https://www.ncbi.nlm.nih.gov/pubmed/22859948
http://dx.doi.org/10.1371/journal.pone.0040487