Pulmonary Infection with Influenza A Virus Induces Site-Specific Germinal Center and T Follicular Helper Cell Responses

Protection from influenza A virus (IAV) challenge requires switched, high affinity Abs derived from long-lived memory B cells and plasma cells. These B cell subsets are generated in germinal centers (GCs), hallmark structures of T helper cell-driven B cell immunity. A full understanding of the GC re...

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Detalles Bibliográficos
Autores principales: Boyden, Alexander W., Legge, Kevin L., Waldschmidt, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394713/
https://www.ncbi.nlm.nih.gov/pubmed/22792401
http://dx.doi.org/10.1371/journal.pone.0040733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394713/
https://www.ncbi.nlm.nih.gov/pubmed/22792401
http://dx.doi.org/10.1371/journal.pone.0040733

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