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Staphylococcus aureus Protein A Plays a Critical Role in Mediating Bone Destruction and Bone Loss in Osteomyelitis

Staphylococcus aureus is the most frequent causative organism of osteomyelitis. It is characterised by widespread bone loss and bone destruction. Previously we demonstrated that S. aureus protein A (SpA) is capable of binding to tumour necrosis factor receptor-1 expressed on pre-osteoblastic cells,...

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Detalles Bibliográficos
Autores principales: Widaa, Amro, Claro, Tania, Foster, Timothy J., O’Brien, Fergal J., Kerrigan, Steven W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394727/
https://www.ncbi.nlm.nih.gov/pubmed/22792377
http://dx.doi.org/10.1371/journal.pone.0040586