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2-Color Calcium Pump Reveals Closure of the Cytoplasmic Headpiece with Calcium Binding

The sarco(endo)plasmic reticulum calcium ATPase (SERCA) undergoes conformational changes while transporting calcium, but the details of the domain motions are still unclear. The objective of the present study was to measure distances between the cytoplasmic domains of SERCA2a in order to reveal the...

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Detalles Bibliográficos
Autores principales: Hou, Zhanjia, Hu, Zhihong, Blackwell, Daniel J., Miller, Tyler D., Thomas, David D., Robia, Seth L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394785/
https://www.ncbi.nlm.nih.gov/pubmed/22808146
http://dx.doi.org/10.1371/journal.pone.0040369