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2-Color Calcium Pump Reveals Closure of the Cytoplasmic Headpiece with Calcium Binding
The sarco(endo)plasmic reticulum calcium ATPase (SERCA) undergoes conformational changes while transporting calcium, but the details of the domain motions are still unclear. The objective of the present study was to measure distances between the cytoplasmic domains of SERCA2a in order to reveal the...
Autores principales: | Hou, Zhanjia, Hu, Zhihong, Blackwell, Daniel J., Miller, Tyler D., Thomas, David D., Robia, Seth L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394785/ https://www.ncbi.nlm.nih.gov/pubmed/22808146 http://dx.doi.org/10.1371/journal.pone.0040369 |
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