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Methylation of the calcium channel regulatory subunit α2δ-3 (CACNA2D3) predicts site-specific relapse in oestrogen receptor-positive primary breast carcinomas

BACKGROUND: Calcium is an important intracellular messenger that mediates many biological processes that are relevant to the malignant process. Calcium ion channels are key in controlling the intracellular calcium, and little is known about their role in human cancer. METHODS: We used qPCR and pyros...

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Detalles Bibliográficos
Autores principales: Palmieri, C, Rudraraju, B, Monteverde, M, Lattanzio, L, Gojis, O, Brizio, R, Garrone, O, Merlano, M, Syed, N, Lo Nigro, C, Crook, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394973/
https://www.ncbi.nlm.nih.gov/pubmed/22644305
http://dx.doi.org/10.1038/bjc.2012.231