Mixed lineage leukaemia-4 regulates cell-cycle progression and cell viability and its depletion suppresses growth of xenografted tumour in vivo

BACKGROUND: Mixed lineage leukaemia-4 (MLL4) is one of the MLL family of histone H3 lysine-4 (H3K4)-specific methyl transferases that have critical roles in gene expression and epigenetics in human. Though MLLs are well recognised as crucial players in histone methylation and gene regulation; little...

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Detalles Bibliográficos
Autores principales: Ansari, K I, Kasiri, S, Mishra, B P, Mandal, S S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394987/
https://www.ncbi.nlm.nih.gov/pubmed/22713656
http://dx.doi.org/10.1038/bjc.2012.263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394987/
https://www.ncbi.nlm.nih.gov/pubmed/22713656
http://dx.doi.org/10.1038/bjc.2012.263

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