Sub-Nanomolar Sensitivity of Nitric Oxide Mediated Regulation of cGMP and Vasomotor Reactivity in Vascular Smooth Muscle

Nitric oxide (NO) is a potent dilator of vascular smooth muscle (VSM) by modulating intracellular cGMP ([cGMP](i)) through the binding and activation of receptor guanylyl cylases (sGC). The kinetic relationship of NO and sGC, as well as the subsequent regulation of [cGMP](i) and its effects on blood...

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Detalles Bibliográficos
Autores principales: Held, Kara F., Dostmann, Wolfgang R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395022/
https://www.ncbi.nlm.nih.gov/pubmed/22807915
http://dx.doi.org/10.3389/fphar.2012.00130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395022/
https://www.ncbi.nlm.nih.gov/pubmed/22807915
http://dx.doi.org/10.3389/fphar.2012.00130

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