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On the Pro-Metastatic Stress Response to Cancer Therapies: Evidence for a Positive Co-Operation between TIMP-1, HIF-1α, and miR-210

In contrast to expectations in the past that tumor starvation or unselective inhibition of proteolytic activity would cure cancer, there is accumulating evidence that microenvironmental stress, such as hypoxia or broad-spectrum inhibition of metalloproteinases can promote metastasis. In fact, malign...

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Detalles Bibliográficos
Autores principales: Cui, Haissi, Grosso, Sebastien, Schelter, Florian, Mari, Bernard, Krüger, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395024/
https://www.ncbi.nlm.nih.gov/pubmed/22807917
http://dx.doi.org/10.3389/fphar.2012.00134