Thimerosal-Derived Ethylmercury Is a Mitochondrial Toxin in Human Astrocytes: Possible Role of Fenton Chemistry in the Oxidation and Breakage of mtDNA

Thimerosal generates ethylmercury in aqueous solution and is widely used as preservative. We have investigated the toxicology of Thimerosal in normal human astrocytes, paying particular attention to mitochondrial function and the generation of specific oxidants. We find that ethylmercury not only in...

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Detalles Bibliográficos
Autores principales: Sharpe, Martyn A., Livingston, Andrew D., Baskin, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395253/
https://www.ncbi.nlm.nih.gov/pubmed/22811707
http://dx.doi.org/10.1155/2012/373678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395253/
https://www.ncbi.nlm.nih.gov/pubmed/22811707
http://dx.doi.org/10.1155/2012/373678

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