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Lumbar Facet Joint Compressive Injury Induces Lasting Changes in Local Structure, Nociceptive Scores, and Inflammatory Mediators in a Novel Rat Model

Objective. To develop a novel animal model of persisting lumbar facet joint pain. Methods. Sprague Dawley rats were anaesthetized and the right lumbar (L5/L6) facet joint was exposed and compressed to ~1 mm with modified clamps applied for three minutes; sham-operated and naïve animals were used as...

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Detalles Bibliográficos
Autores principales: Henry, James L., Yashpal, Kiran, Vernon, Howard, Kim, Jaesung, Im, Hee-Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395270/
https://www.ncbi.nlm.nih.gov/pubmed/22966427
http://dx.doi.org/10.1155/2012/127636