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Structural Basis for the ABO Blood-Group Dependence of Plasmodium falciparum Rosetting

The ABO blood group influences susceptibility to severe Plasmodium falciparum malaria. Recent evidence indicates that the protective effect of group O operates by virtue of reduced rosetting of infected red blood cells (iRBCs) with uninfected RBCs. Rosetting is mediated by a subgroup of PfEMP1 adhes...

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Detalles Bibliográficos
Autores principales: Vigan-Womas, Inès, Guillotte, Micheline, Juillerat, Alexandre, Hessel, Audrey, Raynal, Bertrand, England, Patrick, Cohen, Jacques H., Bertrand, Olivier, Peyrard, Thierry, Bentley, Graham A., Lewit-Bentley, Anita, Mercereau-Puijalon, Odile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395597/
https://www.ncbi.nlm.nih.gov/pubmed/22807674
http://dx.doi.org/10.1371/journal.ppat.1002781