Heme Uptake by Leishmania amazonensis Is Mediated by the Transmembrane Protein LHR1

Trypanosomatid protozoan parasites lack a functional heme biosynthetic pathway, so must acquire heme from the environment to survive. However, the molecular pathway responsible for heme acquisition by these organisms is unknown. Here we show that L. amazonensis LHR1, a homolog of the C. elegans plas...

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Detalles Bibliográficos
Autores principales: Huynh, Chau, Yuan, Xiaojing, Miguel, Danilo C., Renberg, Rebecca L., Protchenko, Olga, Philpott, Caroline C., Hamza, Iqbal, Andrews, Norma W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395602/
https://www.ncbi.nlm.nih.gov/pubmed/22807677
http://dx.doi.org/10.1371/journal.ppat.1002795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395602/
https://www.ncbi.nlm.nih.gov/pubmed/22807677
http://dx.doi.org/10.1371/journal.ppat.1002795

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