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The Receptor Slamf1 on the Surface of Myeloid Lineage Cells Controls Susceptibility to Infection by Trypanosoma cruzi

Trypanosoma cruzi, the protozoan parasite responsible for Chagas' disease, causes severe myocarditis often resulting in death. Here, we report that Slamf1−/− mice, which lack the hematopoietic cell surface receptor Slamf1, are completely protected from an acute lethal parasite challenge. Cardia...

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Detalles Bibliográficos
Autores principales: Calderón, Jossela, Maganto-Garcia, Elena, Punzón, Carmen, Carrión, Javier, Terhorst, Cox, Fresno, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395606/
https://www.ncbi.nlm.nih.gov/pubmed/22807679
http://dx.doi.org/10.1371/journal.ppat.1002799