Efficiency and Power as a Function of Sequence Coverage, SNP Array Density, and Imputation

High coverage whole genome sequencing provides near complete information about genetic variation. However, other technologies can be more efficient in some settings by (a) reducing redundant coverage within samples and (b) exploiting patterns of genetic variation across samples. To characterize as m...

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Detalles Bibliográficos
Autores principales: Flannick, Jason, Korn, Joshua M., Fontanillas, Pierre, Grant, George B., Banks, Eric, Depristo, Mark A., Altshuler, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395607/
https://www.ncbi.nlm.nih.gov/pubmed/22807667
http://dx.doi.org/10.1371/journal.pcbi.1002604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395607/
https://www.ncbi.nlm.nih.gov/pubmed/22807667
http://dx.doi.org/10.1371/journal.pcbi.1002604

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