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Efficiency and Power as a Function of Sequence Coverage, SNP Array Density, and Imputation
High coverage whole genome sequencing provides near complete information about genetic variation. However, other technologies can be more efficient in some settings by (a) reducing redundant coverage within samples and (b) exploiting patterns of genetic variation across samples. To characterize as m...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395607/ https://www.ncbi.nlm.nih.gov/pubmed/22807667 http://dx.doi.org/10.1371/journal.pcbi.1002604 |