Cargando…
Mechanisms of GnRH-Induced Extracellular Signal-Regulated Kinase Nuclear Localization
Gonadotropin-releasing hormone receptors (GnRHR) mediate activation and nuclear translocation of the extracellular signal regulated kinases 1 and 2 (ERK) by phosphorylation on the TEY motif. This is necessary for GnRH to initiate transcriptional programmes controlling fertility, but mechanisms that...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395631/ https://www.ncbi.nlm.nih.gov/pubmed/22808094 http://dx.doi.org/10.1371/journal.pone.0040077 |