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Detecting Individual Sites Subject to Episodic Diversifying Selection

The imprint of natural selection on protein coding genes is often difficult to identify because selection is frequently transient or episodic, i.e. it affects only a subset of lineages. Existing computational techniques, which are designed to identify sites subject to pervasive selection, may fail t...

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Detalles Bibliográficos
Autores principales: Murrell, Ben, Wertheim, Joel O., Moola, Sasha, Weighill, Thomas, Scheffler, Konrad, Kosakovsky Pond, Sergei L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395634/
https://www.ncbi.nlm.nih.gov/pubmed/22807683
http://dx.doi.org/10.1371/journal.pgen.1002764