Cargando…
Detecting Individual Sites Subject to Episodic Diversifying Selection
The imprint of natural selection on protein coding genes is often difficult to identify because selection is frequently transient or episodic, i.e. it affects only a subset of lineages. Existing computational techniques, which are designed to identify sites subject to pervasive selection, may fail t...
Autores principales: | Murrell, Ben, Wertheim, Joel O., Moola, Sasha, Weighill, Thomas, Scheffler, Konrad, Kosakovsky Pond, Sergei L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395634/ https://www.ncbi.nlm.nih.gov/pubmed/22807683 http://dx.doi.org/10.1371/journal.pgen.1002764 |
Ejemplares similares
-
Modeling HIV-1 Drug Resistance as Episodic Directional Selection
por: Murrell, Ben, et al.
Publicado: (2012) -
On the Validity of Evolutionary Models with Site-Specific Parameters
por: Scheffler, Konrad, et al.
Publicado: (2014) -
Suppressors of RNAi from plant viruses are subject to episodic positive selection
por: Murray, Gemma G. R., et al.
Publicado: (2013) -
Purifying Selection Can Obscure the Ancient Age of Viral Lineages
por: Wertheim, Joel O., et al.
Publicado: (2011) -
Non-Negative Matrix Factorization for Learning Alignment-Specific Models of Protein Evolution
por: Murrell, Ben, et al.
Publicado: (2011)