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Numbl inhibits glioma cell migration and invasion by suppressing TRAF5-mediated NF-κB activation
The Notch signaling regulator Numblike (Numbl) is expressed in the brain, but little is known regarding its role in the pathophysiology of glial cells. In this paper, we report that Numbl expression was down-regulated in high-grade human glioma tissue samples and glioblastoma cell lines. To investig...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395653/ https://www.ncbi.nlm.nih.gov/pubmed/22593207 http://dx.doi.org/10.1091/mbc.E11-09-0805 |