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Calmodulin activation of Aurora-A kinase (AURKA) is required during ciliary disassembly and in mitosis
The centrosomal Aurora-A kinase (AURKA) regulates mitotic progression, and overexpression and hyperactivation of AURKA commonly promotes genomic instability in many tumors. Although most studies of AURKA focus on its role in mitosis, some recent work identified unexpected nonmitotic activities of AU...
Autores principales: | Plotnikova, Olga V., Nikonova, Anna S., Loskutov, Yuri V., Kozyulina, Polina Y., Pugacheva, Elena N., Golemis, Erica A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395655/ https://www.ncbi.nlm.nih.gov/pubmed/22621899 http://dx.doi.org/10.1091/mbc.E11-12-1056 |
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