Calmodulin activation of Aurora-A kinase (AURKA) is required during ciliary disassembly and in mitosis

The centrosomal Aurora-A kinase (AURKA) regulates mitotic progression, and overexpression and hyperactivation of AURKA commonly promotes genomic instability in many tumors. Although most studies of AURKA focus on its role in mitosis, some recent work identified unexpected nonmitotic activities of AU...

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Detalles Bibliográficos
Autores principales: Plotnikova, Olga V., Nikonova, Anna S., Loskutov, Yuri V., Kozyulina, Polina Y., Pugacheva, Elena N., Golemis, Erica A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395655/
https://www.ncbi.nlm.nih.gov/pubmed/22621899
http://dx.doi.org/10.1091/mbc.E11-12-1056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395655/
https://www.ncbi.nlm.nih.gov/pubmed/22621899
http://dx.doi.org/10.1091/mbc.E11-12-1056

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