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Plk1 negatively regulates PRC1 to prevent premature midzone formation before cytokinesis

To achieve mitosis and cytokinesis, microtubules must assemble into distinct structures at different stages of cell division—mitotic spindles to segregate the chromosomes before anaphase and midzones to keep sister genomes apart and guide the cleavage furrow after anaphase. This temporal regulation...

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Detalles Bibliográficos
Autores principales: Hu, Chi-Kuo, Özlü, Nurhan, Coughlin, Margaret, Steen, Judith J., Mitchison, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395659/
https://www.ncbi.nlm.nih.gov/pubmed/22621898
http://dx.doi.org/10.1091/mbc.E12-01-0058