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Plk1 negatively regulates PRC1 to prevent premature midzone formation before cytokinesis
To achieve mitosis and cytokinesis, microtubules must assemble into distinct structures at different stages of cell division—mitotic spindles to segregate the chromosomes before anaphase and midzones to keep sister genomes apart and guide the cleavage furrow after anaphase. This temporal regulation...
Autores principales: | Hu, Chi-Kuo, Özlü, Nurhan, Coughlin, Margaret, Steen, Judith J., Mitchison, Timothy J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395659/ https://www.ncbi.nlm.nih.gov/pubmed/22621898 http://dx.doi.org/10.1091/mbc.E12-01-0058 |
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