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RTEL1 contributes to DNA replication and repair and telomere maintenance

Telomere maintenance and DNA repair are important processes that protect the genome against instability. mRtel1, an essential helicase, is a dominant factor setting telomere length in mice. In addition, mRtel1 is involved in DNA double-strand break repair. The role of mRtel1 in telomere maintenance...

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Detalles Bibliográficos
Autores principales: Uringa, Evert-Jan, Lisaingo, Kathleen, Pickett, Hilda A., Brind'Amour, Julie, Rohde, Jan-Hendrik, Zelensky, Alex, Essers, Jeroen, Lansdorp, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395665/
https://www.ncbi.nlm.nih.gov/pubmed/22593209
http://dx.doi.org/10.1091/mbc.E12-03-0179