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RTEL1 contributes to DNA replication and repair and telomere maintenance
Telomere maintenance and DNA repair are important processes that protect the genome against instability. mRtel1, an essential helicase, is a dominant factor setting telomere length in mice. In addition, mRtel1 is involved in DNA double-strand break repair. The role of mRtel1 in telomere maintenance...
Autores principales: | Uringa, Evert-Jan, Lisaingo, Kathleen, Pickett, Hilda A., Brind'Amour, Julie, Rohde, Jan-Hendrik, Zelensky, Alex, Essers, Jeroen, Lansdorp, Peter M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395665/ https://www.ncbi.nlm.nih.gov/pubmed/22593209 http://dx.doi.org/10.1091/mbc.E12-03-0179 |
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