Genome-Wide Detection of Genes Targeted by Non-Ig Somatic Hypermutation in Lymphoma

The processes of somatic hypermutation (SHM) and class switch recombination introduced by activation-induced cytosine deaminase (AICDA) at the Immunoglobulin (Ig) loci are key steps for creating a pool of diversified antibodies in germinal center B cells (GCBs). Unfortunately, AICDA can also acciden...

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Detalles Bibliográficos
Autores principales: Jiang, Yanwen, Soong, T. David, Wang, Ling, Melnick, Ari M., Elemento, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395700/
https://www.ncbi.nlm.nih.gov/pubmed/22808135
http://dx.doi.org/10.1371/journal.pone.0040332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395700/
https://www.ncbi.nlm.nih.gov/pubmed/22808135
http://dx.doi.org/10.1371/journal.pone.0040332

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