Cargando…

In silico labeling reveals the time-dependent label half-life and transit-time in dynamical systems

BACKGROUND: Mathematical models of dynamical systems facilitate the computation of characteristic properties that are not accessible experimentally. In cell biology, two main properties of interest are (1) the time-period a protein is accessible to other molecules in a certain state - its half-life...

Descripción completa

Detalles Bibliográficos
Autores principales: Maiwald, Thomas, Blumberg, Julie, Raue, Andreas, Hengl, Stefan, Schilling, Marcel, Sy, Sherwin KB, Becker, Verena, Klingmüller, Ursula, Timmer, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395849/
https://www.ncbi.nlm.nih.gov/pubmed/22369292
http://dx.doi.org/10.1186/1752-0509-6-13