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In silico labeling reveals the time-dependent label half-life and transit-time in dynamical systems

BACKGROUND: Mathematical models of dynamical systems facilitate the computation of characteristic properties that are not accessible experimentally. In cell biology, two main properties of interest are (1) the time-period a protein is accessible to other molecules in a certain state - its half-life...

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Detalles Bibliográficos
Autores principales:	Maiwald, Thomas, Blumberg, Julie, Raue, Andreas, Hengl, Stefan, Schilling, Marcel, Sy, Sherwin KB, Becker, Verena, Klingmüller, Ursula, Timmer, Jens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395849/ https://www.ncbi.nlm.nih.gov/pubmed/22369292 http://dx.doi.org/10.1186/1752-0509-6-13

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