Endothelial Cells Derived from the Blood-Brain Barrier and Islets of Langerhans Differ in their Response to the Effects of Bilirubin on Oxidative Stress Under Hyperglycemic Conditions

Unconjugated bilirubin (UCB) is a neurotoxic degradation product of heme. Its toxic effects include induction of apoptosis, and ultimately neuronal cell death. However, at low concentrations, UCB is a potent antioxidant that may protect cells and tissues against oxidative stress by neutralizing toxi...

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Detalles Bibliográficos
Autores principales: Kapitulnik, Jaime, Benaim, Clara, Sasson, Shlomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396126/
https://www.ncbi.nlm.nih.gov/pubmed/22811666
http://dx.doi.org/10.3389/fphar.2012.00131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396126/
https://www.ncbi.nlm.nih.gov/pubmed/22811666
http://dx.doi.org/10.3389/fphar.2012.00131

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