Ethyl pyruvate reduces liver injury at early phase but impairs regeneration at late phase in acetaminophen overdose

INTRODUCTION: Inflammation may critically affect mechanisms of liver injury in acetaminophen (APAP) hepatotoxicity. Kupffer cells (KC) play important roles in inflammation, and KC depletion confers protection at early time points after APAP treatment but can lead to more severe injury at a later tim...

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Detalles Bibliográficos
Autores principales: Yang, Runkuan, Zou, Xiaoping, Koskinen, Marja-Leena, Tenhunen, Jyrki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396240/
https://www.ncbi.nlm.nih.gov/pubmed/22248080
http://dx.doi.org/10.1186/cc11149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396240/
https://www.ncbi.nlm.nih.gov/pubmed/22248080
http://dx.doi.org/10.1186/cc11149

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